3-Phenylpyrrolidine → HCID 131727708, compound

HRID 1431948Notes

Reaction equation

CC1(C)[O:6][C:5](=[O:7])[CH:4]([CH:8]([CH2:12][CH2:13][CH2:14][CH3:15])[C:9]([OH:11])=O)[O:3]1.[C:17]1([CH:23]2[CH2:27][CH2:26][NH:25][CH2:24]2)[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[OH:3][C@@H:4]([C@H:8]([C:9]([N:25]1[CH2:26][CH2:27][CH:23]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[CH2:24]1)=[O:11])[CH2:12][CH2:13][CH2:14][CH3:15])[C:5]([OH:6])=[O:7]

Participants

Reactant 2

HCID 31467433-Phenylpyrrolidine

HCID 22256526HCID 22256526, compound

Product 1

HCID 131727708HCID 131727708, compound

Procedure

The title compound is prepared from 2-(2,2-dimethyl-4-oxo-1,3-dioxolan-5-yl)hexanoic acid B-5 and commercially available 3-phenyl-pyrrolidine A-5 according to General Procedure B.

Sources & evidence

ORD record: ord-00b1c3a720e54615b517efd6b51572bc
Source dataset: uspto-grants-2009_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07612059B2

Reaction notes

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