3-(Pyrrolidin-3-yl)pyridine → HCID 131727709, compound

HRID 1431949Notes

Reaction equation

HRID 1431949 reaction equation
CC1(C)[O:6][C:5](=[O:7])[CH:4]([CH:8]([CH2:12][CH2:13][CH2:14][CH3:15])[C:9]([OH:11])=O)[O:3]1.[NH:17]1[CH2:21][CH2:20][CH:19]([C:22]2[CH:23]=[N:24][CH:25]=[CH:26][CH:27]=2)[CH2:18]1>>[OH:3][C@@H:4]([C@H:8]([C:9]([N:17]1[CH2:21][CH2:20][CH:19]([C:22]2[CH:23]=[N:24][CH:25]=[CH:26][CH:27]=2)[CH2:18]1)=[O:11])[CH2:12][CH2:13][CH2:14][CH3:15])[C:5]([OH:6])=[O:7]

Participants

3

Reactant 2

HCID 36136513-(Pyrrolidin-3-yl)pyridineHCID 22256526HCID 22256526, compound

Product 1

HCID 131727709HCID 131727709, compound

Procedure

The title compound is prepared from 2-(2,2-dimethyl-4-oxo-1,3-dioxolan-5-yl)hexanoic acid B-5 and commercially available 3-pyrrolidin-3-yl-pyridine A-5 according to General Procedure B.

Sources & evidence

ORD record
ord-05822195b40e4fef8b000895bfc577aa
Source dataset
uspto-grants-2009_11
Patent number
US07612059B2

Reaction notes

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