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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1431994Generated: November 2, 2026

(R)-4-azido-3,4-dihydro-2H-chromene-7-carbaldehyde → (R)-N-((4-Azido-3,4-dihydro-2H-chromen-7-yl)methyl)-cyclopentylamine

https://huagongshe.com/reaction/1431994

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-4-azido-3,4-dihydro-2H-chromene-7-carbaldehydeHCID 86604856—
Reactant(R)-1-((5-azido-5,6,7,8-tetrahydronaphthalen-2-yl)methyl)piperidineHCID 86604857—
Product(R)-N-((4-Azido-3,4-dihydro-2H-chromen-7-yl)methyl)-cyclopentylamineHCID 86604859—

Reaction Steps

Using the same procedure described for (20), and using (R)-4-azido-3,4-dihydro-2H-chromene-7-carbaldehyde afforded (R)-N-((4-Azido-3,4-dihydro-2H-chromen-7-yl)methyl)-cyclopentylamine (27) MS (m/z): 273.3 (M+H) (Calc'd for C15H20N4O−272.35).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07612060B2
Source datasetuspto-grants-2009_11
ORD IDord-8cbc7de5a3f44e12bc985e8588fce326
Source noteuspto-grants-2009_11