HCID 86604869, compound → HCID 86604873, compound

HRID 1432009Notes

Reaction equation

HRID 1432009 reaction equation
C1(S(N2CCNC(=O)[C@H]2CC#C)(=O)=O)C=CC=CC=1.[F:20][C:21]([F:42])([F:41])[C:22]1[CH:23]=[C:24]([S:28]([N:31]2[CH:36]=[CH:35][NH:34][C:33](=[O:37])[C@H:32]2[CH2:38][C:39]#[CH:40])(=[O:30])=[O:29])[CH:25]=[CH:26][CH:27]=1>>[CH2:38]([C@H:32]1[N:31]([S:28]([C:24]2[CH:25]=[CH:26][CH:27]=[C:22]([C:21]([F:41])([F:42])[F:20])[CH:23]=2)(=[O:30])=[O:29])[CH2:36][CH2:35][NH:34][C:33]1=[O:37])[C:39]#[CH:40]

Participants

3

Reactant 2

HCID 86604869HCID 86604869, compoundHCID 86604874HCID 86604874, compound

Product 1

HCID 86604873HCID 86604873, compound

Procedure

Using the procedure described for compound 51, (R)-4-(3-trifluoromethylbenzenesulfonyl)-3-(prop-2-ynyl)-3,4-dihydropyrazin-2(1H)-one afforded the title compound as a tan solid.

Sources & evidence

ORD record
ord-8f5673b68fae4bcc8c67009009dd857c
Source dataset
uspto-grants-2009_11
Patent number
US07612060B2

Reaction notes

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