Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Azobisisobutyronitrile | HCID 6547 | — |
| Reactant | 3,5-Dibromotoluene | HCID 15361 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | 3,5-Dibromobenzyl bromide | HCID 143427 | — |
Reaction Steps
Step H1. A mixture of 3,5-dibromo-toluene (4.25 g, 17 mmol), NBS (3 g, 17 mmol), and AIBN (150 mg) in carbon tetrachloride (50 mL) was heated at 80° C. for 3 hours. The resulting mixture was run through a silicon gel column with dichloromethane as the eluant. The fraction was collected and solvent was removed by rotovap, crude 1,3-dibromo-5-(bromomethyl)benzene was obtained as a white residue.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07612069B2 |
|---|
| Source dataset | uspto-grants-2009_11 |
|---|
| ORD ID | ord-5f6af8584f41428590fe1d19723add88 |
|---|
| Source note | uspto-grants-2009_11 |
|---|
