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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1432083Generated: October 27, 2026

(3-(tert-Butyl)phenyl)methanamine → n-((r)-1-Cyano-3-methyl-hept-6-enyl)-acetamide

https://huagongshe.com/reaction/1432083

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3-(tert-Butyl)phenyl)methanamineHCID 8167069—
Reactant3-(Aminomethyl)-5-bromopyridineHCID 22992264—
Reactant(3-Cyclopropylphenyl)methanamineHCID 53400850—
Reactant(5-Cyclopropylpyridin-3-yl)methanamineHCID 55281594—
Reactant2-Cyclopropyl-4-pyridinemethanamineHCID 55285242—
Reactant3-(2,2-Dimethyl-propyl)-benzylamineHCID 68545612—
ReactantIsopropyl-2,2-dimethyl-chroman-4(r/s)-ylamineHCID 81137825—
Productn-((r)-1-Cyano-3-methyl-hept-6-enyl)-acetamideHCID 87490605—

Reaction Steps

The following compounds can be obtained by a similar procedure, using 3-cyclopropyl-benzylamine, C-(5-bromo-pyridine-3-yl)methylamine, C-(5-cyclopropyl-pyridine-3-yl)-methylamine, C-(2-cyclopropyl-pyridine-4-yl)-methylamine, 6 isopropyl-2,2-dimethyl-chroman-4(R/S)-ylamine, 3-tert-butyl-benzylamine or 3-(2,2-dimethyl-propyl)-benzylamine instead of 3-isopropyl-benzylamine:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07612055B2
Source datasetuspto-grants-2009_11
ORD IDord-1eecc42ced82409c8d26a1b7fdb6c051
Source noteuspto-grants-2009_11