HCID 68546525, compound → HCID 68539439, compound

Participants

Reaction Steps

A solution of 199 mg (0.35 mmol) [(3S,6S,14R,16S)-16-((1S,3R)-3-butylcarbamoyl-1-hydroxy-butyl)-3,14-dimethyl-2,5-dioxo-1,4-diaza-cyclohexadec-10-en-6-yl]-carbamic acid tert-butyl ester in 10 ml THF and 10 ml EtOH is stirred in the presence of 20 mg 10% Pd-C under an hydrogen atmosphere for 1 h. The mixture is filtered over a pad of celite and the solvent evaporated. This yields the title compound as a white powder.

Provenance & Evidence