HCID 69065520, compound → HCID 68571703, compound

Participants

Reaction Steps

A solution of 74 mg (0.15 mmol) (2R,4S)-N-butyl-4-(-(3S,6S,8R)-3,8-dimethyl-1,1,4-trioxo-1lambda*6*-thia-5-aza-cyclohexadec-11-en-6-yl)-4-hydroxy-2-methyl-butyramide in 5 ml MeOH is stirred in the presence of 20 mg 10% Pd—C under a hydrogen atmosphere for 1 h. The mixture is filtered over a pad of celite and the solvent evaporated. The residue is crystallized from toluene and the title compound is isolated as a white powder.

Provenance & Evidence