3-Iodobenzyl bromide → (S)-3-(3-Iodo-benzylsulfanyl)-2-methyl-propionic acid

HRID 1432103Notes

Reaction equation

HRID 1432103 reaction equation
C([S:7][CH2:8][C@@H:9]([CH3:13])[C:10]([OH:12])=[O:11])CCCC=C.Br[CH2:15][C:16]1[CH:21]=[CH:20][CH:19]=[C:18]([I:22])[CH:17]=1>>[I:22][C:18]1[CH:17]=[C:16]([CH:21]=[CH:20][CH:19]=1)[CH2:15][S:7][CH2:8][C@@H:9]([CH3:13])[C:10]([OH:12])=[O:11]

Participants

3

Reactant 2

HCID 27593613-Iodobenzyl bromideHCID 86611584(S)-3-hex-5-enylsulfanyl-2-methyl-propionic acid

Product 1

HCID 68543089(S)-3-(3-Iodo-benzylsulfanyl)-2-methyl-propionic acid

Procedure

The title compound is prepared similarly to (S)-3-hex-5-enylsulfanyl-2-methyl-propionic acid (IIa), using 1-bromomethyl-3-iodo-benzene instead of 6-bromo-hex-1-ene.

Sources & evidence

ORD record
ord-616e869da86943f0a5e63776e397faed
Source dataset
uspto-grants-2009_11
Patent number
US07612055B2

Reaction notes

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