HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propanal → HCID 86052041, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propanal | HCID 527 | — |
| Reactant | Boron trifluoride etherate | HCID 8000 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | Methyl Carbamate | HCID 11722 | — |
| Reactant | Allyltrimethylsilane | HCID 69808 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 86052041 | HCID 86052041 | — |
Reaction Steps
To a cooled solution of 11.6 g (0.2 mol) propionaldehyde, 15 g (0.2 mol) carbamic acid methyl ester and 22.92 g allyl trimethyl silane in 200 ml acetonitrile are added dropwise 28.4 g (0.2 mol) boron trifluoride etherate. After the addition the mixture is neutralised with 10% aqueous Na2CO3 and extracted with EtOAc. The organic phase is washed with water, dried with sodium sulfate, evaporated and distilled at 1 mbar, yielding the title compound as a colorless liquid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07612055B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-afad189e8a534939ab75fea4ad0ea4ca |
| Source note | uspto-grants-2009_11 |