HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-5,6-dimethylthieno(2,3-d)pyrimidine → HCID 11530562, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-5,6-dimethylthieno(2,3-d)pyrimidine | HCID 290212 | — |
| Reactant | 4-Piperidinamine, 1-(cyclohexylmethyl)-, hydrochloride (1:2) | HCID 53255886 | — |
| Product | HCID 11530562 | HCID 11530562 | — |
Reaction Steps
The title compound was prepared (81 mg, 28%) from 4-chloro-5,6-dimethylthieno[2,3-d]pyrimidine (325 mg, 1.21 mmol) and 1-(cyclohexylmethyl)piperidin-4-amine dihydrochloride (160 mg, 0.81 mmol) by following the general procedure described for Preparation 6. 1H NMR (400 MHz, CDCl3) δ 8.36 (s, 1H), 5.36 (d, 1H), 4.22 (m, 1H), 2.80 (d, 2H), 2.44 (s, 3H), 2.41 (s, 3H), 2.21-2.09 (m, 7H), 1.79-1.45 (m, 6H), 1.20 (m, 4H), 0.88 (m, 2H); MS (ESI) m/z: Calculated for C20H31N4S, 359.23; Observed: 359.2 (M++1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07612078B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-b1bc316497eb4c5e98b5a963673258d9 |
| Source note | uspto-grants-2009_11 |