HRID1432335

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：C[C@@H]1C[C@@H]([C@H](Cc2cccc(OCc3ccccc3)c2)NC(=O)OC(C)(C)C)OC1=O

HCID11495571

未命名化合物

PRODUCTS

生成物

结构：CCCCNC(=O)[C@H](C)C[C@H](O)[C@H](Cc1cccc(OCc2ccccc2)c1)NC(=O)OC(C)(C)C

HCID11648991

未命名化合物

收率 188.6%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID8007

Butylamine

C4H11N

CONDITIONS

反应条件

温度: 90 °C

PROCEDURE

实验过程

[(S*)-2-(3-Benzyloxy-phenyl)-1-((2S*,4R*)-4-methyl-5-oxo-tetrahydro-furan-2-yl)-ethyl]-carbamic acid tert-butyl ester (4.0 g, 9.4 mmol) is dissolved in butylamine (200 ml) and stirred for 18 h in an heating bath of 90° C. The butylamine is evaporated and the residue is recrystallized from DCM/ether/hexane to give white crystals (4.42 g).

WORKUP

后处理

customThe butylamine is evaporated
customthe residue is recrystallized from DCM/ether/hexane