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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1432446Generated: October 25, 2026

Benzaldehyde → N-(2-{2-[(4-Hydroxy-5-isopropyl-2-oxo-2,5-dihydro-1H-pyrrol-3-yl)-phenyl-methyl]-1H-indol-3-yl}-ethyl)-benzamide

https://huagongshe.com/reaction/1432446

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzaldehydeHCID 240—
ReactantN-(2-(1H-indol-3-yl)ethyl)benzamideHCID 684658—
Reactant4-Hydroxy-5-isopropyl-1,5-dihydro-pyrrol-2-oneHCID 56604111—
ProductN-(2-{2-[(4-Hydroxy-5-isopropyl-2-oxo-2,5-dihydro-1H-pyrrol-3-yl)-phenyl-methyl]-1H-indol-3-yl}-ethyl)-benzamideHCID 57933477—

Reaction Steps

Using general procedure C, 4-hydroxy-5-isopropyl-1,5-dihydro-pyrrol-2-one (Lit. 11) was reacted with benzaldehyde and N-[2-(1H-indol-3-yl)-ethyl]-benzamide to give the title compound as a grey solid. MS: 494.3 ([M+H]+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07612099B2
Source datasetuspto-grants-2009_11
ORD IDord-f2d04eca26d342a29e50d8e5a0668bc8
Source noteuspto-grants-2009_11