HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Benzaldehyde → 3-[(5-Fluoro-3-methyl-1H-indol-2-yl)-phenyl-methyl]-4-hydroxy-5-isopropyl-1,5-dihydro-pyrrol-2-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Benzaldehyde | HCID 240 | — |
| Edukt | 5-Fluoro-3-methyl-1H-indole | HCID 22351503 | — |
| Edukt | 4-Hydroxy-5-isopropyl-1,5-dihydro-pyrrol-2-one | HCID 56604111 | — |
| Produkt | 3-[(5-Fluoro-3-methyl-1H-indol-2-yl)-phenyl-methyl]-4-hydroxy-5-isopropyl-1,5-dihydro-pyrrol-2-one | HCID 57933431 | — |
Reaktionsschritte
Using general procedure C, 4-hydroxy-5-isopropyl-1,5-dihydro-pyrrol-2-one (Lit. 11) was reacted with benzaldehyde and 5-fluoro-3-methyl-1H-indole to give the title compound as a yellow solid. MS: 377.1 ([M−H]−).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07612099B2 |
| Quelldatensatz | uspto-grants-2009_11 |
| ORD ID | ord-3c0af067d68741ff8a9bf7a325a16482 |
| Quellennotiz | uspto-grants-2009_11 |