HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isobutyraldehyde → N-(2-{2-[1-(5-Benzyl-4-hydroxy-2-oxo-2,5-dihydro-furan-3-yl)-2-methyl-propyl]-1H-indol-3-yl}-ethyl)-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isobutyraldehyde | HCID 6561 | — |
| Reactant | N-Acetyltryptamine | HCID 70547 | — |
| Reactant | 5-benzyl-4-hydroxy-5H-furan-2-one | HCID 69063555 | — |
| Product | N-(2-{2-[1-(5-Benzyl-4-hydroxy-2-oxo-2,5-dihydro-furan-3-yl)-2-methyl-propyl]-1H-indol-3-yl}-ethyl)-acetamide | HCID 57933453 | — |
Reaction Steps
Using general procedure C, 5-benzyl-4-hydroxy-5H-furan-2-one (Lit. 13) was reacted with 2-methyl-propionaldehyde and N-[2-(1H-indol-3-yl)-ethyl]-acetamide) to give the title compound as a yellow solid. MS: 445.1 ([M−H]−).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07612099B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-453a3908d3dd4f30a72463a9d9015cbe |
| Source note | uspto-grants-2009_11 |