N-Acetyltryptamine → N-(2-{2-[1-(5-Benzyl-4-hydroxy-2-oxo-2,5-dihydro-furan-3-yl)-3-methyl-butyl]-1H-indol-3-yl}-ethyl)-acetamide

Participants

Role	Name	HCID	Charge
Reactant	N-Acetyltryptamine	HCID 70547	—
Reactant	5-benzyl-4-hydroxy-5H-furan-2-one	HCID 69063555	—
Product	N-(2-{2-[1-(5-Benzyl-4-hydroxy-2-oxo-2,5-dihydro-furan-3-yl)-3-methyl-butyl]-1H-indol-3-yl}-ethyl)-acetamide	HCID 57933434	—

Reaction Steps

Using general procedure C, 5-benzyl-4-hydroxy-5H-furan-2-one (Lit. 13) was reacted with 3-methyl-butyraldehydeand and N-[2-(1H-indol-3-yl)-ethyl]-acetamide) to give the title compound as a yellow solid. MS: 459.1 ([M−H ]−).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07612099B2
Source dataset	uspto-grants-2009_11
ORD ID	ord-4aa6bda5f28d4d51950f0da8a65c3597
Source note	uspto-grants-2009_11