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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1432461Generated: November 4, 2026

Pentanal → N-(2-{2-[1-(5-Benzyl-4-hydroxy-2-oxo-2,5-dihydro-furan-3-yl)-pentyl]-1H-indol-3-yl}-ethyl)-acetamide

https://huagongshe.com/reaction/1432461

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPentanalHCID 8063—
ReactantN-AcetyltryptamineHCID 70547—
Reactant5-benzyl-4-hydroxy-5H-furan-2-oneHCID 69063555—
ProductN-(2-{2-[1-(5-Benzyl-4-hydroxy-2-oxo-2,5-dihydro-furan-3-yl)-pentyl]-1H-indol-3-yl}-ethyl)-acetamideHCID 57933416—

Reaction Steps

Using general procedure C, 5-benzyl-4-hydroxy-5H-furan-2-one (Lit. 13) was reacted with pentanal and N-[2-(1H-indol-3-yl)-ethyl]-acetamide) to give the title compound as a white solid. MS: 459.3 ([M−H]−).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07612099B2
Source datasetuspto-grants-2009_11
ORD IDord-0b4ea8abbf3f4bcbb07162373027640f
Source noteuspto-grants-2009_11