HRID1432463

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7707

3-Phenylpropanal

C9H10O

HCID70547

N-Acetyltryptamine

C12H14N2O

HCID69063555

未命名化合物

PRODUCTS

生成物

结构：CC(=O)NCCc1c(C(CCc2ccccc2)C2=C(O)C(Cc3ccccc3)OC2=O)[nH]c2ccccc12

HCID57933459

未命名化合物

PROCEDURE

实验过程

Using general procedure C, 5-benzyl-4-hydroxy-5H-furan-2-one (Lit. 13) was reacted with 3-phenyl-propionaldehyde and N-[2-(1H-indol-3-yl)-ethyl]-acetamide) to give the title compound as a yellow solid. MS: 507.2 ([M−H]−).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-0f6946673b1b45daaaeaceb9b1272008
来源数据集: uspto-grants-2009_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07612099B2
来源说明: uspto-grants-2009_11

反应 SMILES

[CH2:1]([CH:8]1[O:12][C:11](=[O:13])[CH:10]=[C:9]1[OH:14])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:15]1([CH2:21][CH2:22][CH:23]=O)[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1.[NH:25]1[C:33]2[C:28](=[CH:29][CH:30]=[CH:31][CH:32]=2)[C:27]([CH2:34][CH2:35][NH:36][C:37](=[O:39])[CH3:38])=[CH:26]1>>[CH2:1]([CH:8]1[O:12][C:11](=[O:13])[C:10]([CH:23]([C:26]2[NH:25][C:33]3[C:28]([C:27]=2[CH2:34][CH2:35][NH:36][C:37](=[O:39])[CH3:38])=[CH:29][CH:30]=[CH:31][CH:32]=3)[CH2:22][CH2:21][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)=[C:9]1[OH:14])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1