HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzaldehyde → 3-{[3-(2-Amino-ethyl)-6-ethyl-1H-indol-2-yl]-phenyl-methyl}-4-hydroxy-5-phenyl-5H-furan-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzaldehyde | HCID 240 | — |
| Reactant | 4-Hydroxy-5-phenylfuran-2(5H)-one | HCID 54694569 | — |
| Reactant | 2-(6-ethyl-1H-indol-3-yl)-ethylamine | HCID 69070064 | — |
| Product | 3-{[3-(2-Amino-ethyl)-6-ethyl-1H-indol-2-yl]-phenyl-methyl}-4-hydroxy-5-phenyl-5H-furan-2-one | HCID 57933436 | — |
Reaction Steps
Using general procedure C, 4-hydroxy-5-phenyl-5H-furan-2-one (Lit. 14) was reacted with benzaldehyde and 2-(6-ethyl-1H-indol-3-yl)-ethylamine (Lit. 8) to give the title compound as a white solid; MS: 453.3 ([M+H]+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07612099B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-58fb7aa166fb43fe9e38987cf541ebc1 |
| Source note | uspto-grants-2009_11 |