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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1432479Generated: November 2, 2026

Benzaldehyde → N-(2-{2-[(2-Hydroxy-5-oxo-3-phenyl-cyclopent-1-enyl)-phenyl-methyl]-1H-indol-3-yl}-ethyl)-acetamide

https://huagongshe.com/reaction/1432479

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzaldehydeHCID 240—
ReactantN-AcetyltryptamineHCID 70547—
Reactant3-Hydroxy-4-phenyl-cyclopent-2-enoneHCID 69069664—
ProductN-(2-{2-[(2-Hydroxy-5-oxo-3-phenyl-cyclopent-1-enyl)-phenyl-methyl]-1H-indol-3-yl}-ethyl)-acetamideHCID 57933418—

Reaction Steps

Using general procedure C, 3-hydroxy-4-phenyl-cyclopent-2-enone (Lit. 17) was reacted with benzaldehyde and N-[2-(1H-indol-3-yl)-ethyl]-acetamide to give the title compound as a pink solid. MS: 465.0 ([M+H]+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07612099B2
Source datasetuspto-grants-2009_11
ORD IDord-9d056e0d58964ef3940201d7535240d2
Source noteuspto-grants-2009_11