HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzaldehyde → N-(2-{6-Fluoro-2-[(2-hydroxy-5-oxo-3-phenyl-cyclopent-1-enyl)-phenyl-methyl]-1H-indol-3-yl}-ethyl)-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzaldehyde | HCID 240 | — |
| Reactant | N-[2-(6-Fluoro-1H-indol-3-yl)-ethyl]-acetamide | HCID 10751398 | — |
| Reactant | 3-Hydroxy-4-phenyl-cyclopent-2-enone | HCID 69069664 | — |
| Product | N-(2-{6-Fluoro-2-[(2-hydroxy-5-oxo-3-phenyl-cyclopent-1-enyl)-phenyl-methyl]-1H-indol-3-yl}-ethyl)-acetamide | HCID 57933474 | — |
Reaction Steps
Using general procedure C, 3-hydroxy-4-phenyl-cyclopent-2-enone (Lit. 17) was reacted with benzaldehyde and N-[2-(6-fluoro-1H-indol-3-yl)-ethyl]-acetamide (Example 18.1.) to give the title compound as a pink solid. MS: 483.5 ([M+H]+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07612099B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-36dea28d0ae24a2d82cfb32f4808eb6d |
| Source note | uspto-grants-2009_11 |