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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1432481Generated: November 4, 2026

2-Pyridinecarboxaldehyde → N-(2-{2-[(2-Hydroxy-5-oxo-3-phenyl-cyclopent-1-enyl)-pyridin-2-yl-methyl]-1H-indol-3-yl}-ethyl)-acetamide

https://huagongshe.com/reaction/1432481

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-PyridinecarboxaldehydeHCID 14273—
ReactantN-AcetyltryptamineHCID 70547—
Reactant3-Hydroxy-4-phenyl-cyclopent-2-enoneHCID 69069664—
ProductN-(2-{2-[(2-Hydroxy-5-oxo-3-phenyl-cyclopent-1-enyl)-pyridin-2-yl-methyl]-1H-indol-3-yl}-ethyl)-acetamideHCID 57933428—

Reaction Steps

Using general procedure C, 3-hydroxy-4-phenyl-cyclopent-2-enone (Lit. 17) was reacted with pyridine-2-carbaldehyde and N-[2-(1H-indol-3-yl)-ethyl]-acetamide to give the title compound as a white solid. MS: 466.3 ([M+H]+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07612099B2
Source datasetuspto-grants-2009_11
ORD IDord-4b2994c1363248d9bc32d341930e5f07
Source noteuspto-grants-2009_11