N-Acetyltryptamine → HCID 178474660, compound

HRID 1432483Notes

Reaction equation

HRID 1432483 reaction equation
[OH:1][C:2]1[CH:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[CH2:5][C:4](=[O:13])[CH:3]=1.[N:14]1[CH:18]=[C:17]([CH:19]=O)[NH:16][CH:15]=1.[NH:21]1[C:29]2[C:24](=[CH:25][CH:26]=[CH:27][CH:28]=2)[C:23]([CH2:30][CH2:31][NH:32][C:33](=[O:35])[CH3:34])=[CH:22]1>>[OH:1][C:2]1[CH:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[CH2:5][C:4](=[O:13])[C:3]=1[CH:19]([C:17]1[N:16]=[CH:15][NH:14][CH:18]=1)[C:22]1[NH:21][C:29]2[C:24]([C:23]=1[CH2:30][CH2:31][NH:32][C:33](=[O:35])[CH3:34])=[CH:25][CH:26]=[CH:27][CH:28]=2

Participants

4

Reactant 3

HCID 70547N-AcetyltryptamineHCID 764281H-Imidazole-4-carbaldehydeHCID 690696643-Hydroxy-4-phenyl-cyclopent-2-enone

Product 1

HCID 178474660HCID 178474660, compound

Procedure

Using general procedure C, 3-hydroxy-4-phenyl-cyclopent-2-enone (Lit. 17) was reacted with 3H-imidazole-4-carbaldehyde and N-[2-(1H-indol-3-yl)-ethyl]-acetamide to give the title compound as pale brown solid. MS: 455.0 ([M+H]+).

Sources & evidence

ORD record
ord-5209fb52d5ac41c5a2edbe10c02d3163
Source dataset
uspto-grants-2009_11
Patent number
US07612099B2

Reaction notes

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