HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-imidazole-2-carbaldehyde → N-(2-{2-[(2-Hydroxy-5-oxo-3-phenyl-cydopent-1-enyl)-(1H-imidazol-2-yl)-methyl]-1H-indol-3-yl}-ethyl)-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-imidazole-2-carbaldehyde | HCID 24955 | — |
| Reactant | N-Acetyltryptamine | HCID 70547 | — |
| Reactant | 3-Hydroxy-4-phenyl-cyclopent-2-enone | HCID 69069664 | — |
| Product | N-(2-{2-[(2-Hydroxy-5-oxo-3-phenyl-cydopent-1-enyl)-(1H-imidazol-2-yl)-methyl]-1H-indol-3-yl}-ethyl)-acetamide | HCID 57933442 | — |
Reaction Steps
Using general procedure C, 3-hydroxy-4-phenyl-cyclopent-2-enone (Lit. 17) was reacted with 1H-imidazole-2-carbaldehyde and N-[2-(1H-indol-3-yl)-ethyl]-acetamide to give the title compound as pale brown solid. MS: 455.0 ([M+H]+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07612099B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-b8c05baa57e543deb60d8c84a1ed4d75 |
| Source note | uspto-grants-2009_11 |