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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1432485Generated: November 2, 2026

Benzaldehyde → N-(2-{5-Ethyl-2-[(2-hydroxy-5-oxo-3-phenyl-cyclopent-1-enyl)-phenyl-methyl]-1H-indol-3-yl}-ethyl)-acetamide

https://huagongshe.com/reaction/1432485

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzaldehydeHCID 240—
ReactantN-[2-(5-Ethyl-1H-indol-3-yl)ethyl]acetamideHCID 45095775—
Reactant3-Hydroxy-4-phenyl-cyclopent-2-enoneHCID 69069664—
ProductN-(2-{5-Ethyl-2-[(2-hydroxy-5-oxo-3-phenyl-cyclopent-1-enyl)-phenyl-methyl]-1H-indol-3-yl}-ethyl)-acetamideHCID 57933448—

Reaction Steps

Using general procedure C, 3-hydroxy-4-phenyl-cyclopent-2-enone (Lit. 17) was reacted with benzaldehyde and N-[2-(5-ethyl-1H-indol-3-yl)-ethyl]-acetamide (Lit. 6) to give the title compound as an orange solid. MS: 493.4 ([M+H]+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07612099B2
Source datasetuspto-grants-2009_11
ORD IDord-ad6dc6eb77154f9da91cac3d541910ad
Source noteuspto-grants-2009_11