HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzaldehyde → 2-{[3-(2-Amino-ethyl)-5-methyl-1H-indol-2-yl]-phenyl-methyl}-3-hydroxy-4-phenyl-cyclopent-2-enone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzaldehyde | HCID 240 | — |
| Reactant | 1H-Indole-3-ethanamine, 5-ethyl- | HCID 188006 | — |
| Reactant | 3-Hydroxy-4-phenyl-cyclopent-2-enone | HCID 69069664 | — |
| Product | 2-{[3-(2-Amino-ethyl)-5-methyl-1H-indol-2-yl]-phenyl-methyl}-3-hydroxy-4-phenyl-cyclopent-2-enone | HCID 57933408 | — |
Reaction Steps
Using general procedure C, 3-hydroxy-4-phenyl-cyclopent-2-enone (Lit. 17) was reacted with benzaldehyde and 2-(5-ethyl-1H-indol-3-yl)-ethylamine to give the title compound as orange solid. MS: 437.1 ([M+H]+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07612099B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-4d4e091a14d5406c9c8c8f1fba2b8398 |
| Source note | uspto-grants-2009_11 |