Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1432487Generated: November 2, 2026

Benzaldehyde → N-(2-{2-[(2-Hydroxy-5-oxo-3-phenyl-cyclopent-1-enyl)-phenyl-methyl]-5-methyl-1H-indol-3-yl}-ethyl)-acetamide

https://huagongshe.com/reaction/1432487

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzaldehydeHCID 240—
ReactantN-[2-(5-methyl-1H-indol-3-yl)ethyl]acetamideHCID 699129—
Reactant3-Hydroxy-4-phenyl-cyclopent-2-enoneHCID 69069664—
ProductN-(2-{2-[(2-Hydroxy-5-oxo-3-phenyl-cyclopent-1-enyl)-phenyl-methyl]-5-methyl-1H-indol-3-yl}-ethyl)-acetamideHCID 57933433—

Reaction Steps

Using general procedure C, 3-hydroxy-4-phenyl-cyclopent-2-enone (Lit. 17) was reacted with benzaldehyde and N-[2-(5-methyl-1H-indol-3-yl)-ethyl]-acetamide (Lit. 7) to give the title compound as orange solid. MS: 479.0 ([M+H]+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07612099B2
Source datasetuspto-grants-2009_11
ORD IDord-2791d43853664028b10ddeb493a6b40a
Source noteuspto-grants-2009_11