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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1432488Generated: November 3, 2026

Benzaldehyde → 2-{[3-(2-Amino-ethyl)-6-ethyl-1H-indol-2-yl]-phenyl-methyl}-3-hydroxy-4-phenyl-cyclopent-2-enone

https://huagongshe.com/reaction/1432488

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzaldehydeHCID 240—
Reactant3-Hydroxy-4-phenyl-cyclopent-2-enoneHCID 69069664—
Reactant2-(6-ethyl-1H-indol-3-yl)-ethylamineHCID 69070064—
Product2-{[3-(2-Amino-ethyl)-6-ethyl-1H-indol-2-yl]-phenyl-methyl}-3-hydroxy-4-phenyl-cyclopent-2-enoneHCID 57933445—

Reaction Steps

Using general procedure C, 3-hydroxy-4-phenyl-cyclopent-2-enone (Lit. 17) was reacted with benzaldehyde and 2-(6-ethyl-1H-indol-3-yl)-ethylamine (Lit. 8) to give the title compound as a pale brown solid. MS: 451.0 ([M+H]+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07612099B2
Source datasetuspto-grants-2009_11
ORD IDord-64249a88e9c649b5a4d6ea15e32a0173
Source noteuspto-grants-2009_11