HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Benzaldehyde → (R)-3-[(5-Fluoro-3-methyl-1H-indol-2-yl)-phenyl-methyl]-4-hydroxy-5-methyl-5-phenyl-1,5-dihydro-pyrrol-2-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Benzaldehyde | HCID 240 | — |
| Edukt | 5-Fluoro-3-methyl-1H-indole | HCID 22351503 | — |
| Edukt | (R)-4-hydroxy-5-methyl-5-phenyl-1,5-dihydro-pyrrol-2-one | HCID 69071890 | — |
| Produkt | (R)-3-[(5-Fluoro-3-methyl-1H-indol-2-yl)-phenyl-methyl]-4-hydroxy-5-methyl-5-phenyl-1,5-dihydro-pyrrol-2-one | HCID 57933413 | — |
Reaktionsschritte
Using general procedure D, (R)-4-hydroxy-5-methyl-5-phenyl-1,5-dihydro-pyrrol-2-one (prepared according to Lit. 11, see also Lit. 19) was reacted with benzaldehyde and 5-fluoro-3-methyl-1H-indole to give the title compound as a pale yellow foam. MS: 425.4 ([M−H]−).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07612099B2 |
| Quelldatensatz | uspto-grants-2009_11 |
| ORD ID | ord-dd5f810426d849fc833a2ed06f8244c1 |
| Quellennotiz | uspto-grants-2009_11 |