HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → HCID 68949812, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | HCID 68949662 | HCID 68949662 | — |
| Reactant | HCID 68952553 | HCID 68952553 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 68949812 | HCID 68949812 | — |
Reaction Steps
0.57 g of bromo-N—(N-BOC-valyl)-piperidin-3-ol, dissolved in pyridine, is treated with 0.4 ml of acetic acid anhydride, the mixture obtained is stirred and a mixture of 3(R*)-acetoxy-4(R*)-bromo-N—(N-BOC-(R)-valyl)-piperidine (COMPOUND A) and 3(S*)-acetoxy-4(S*)-bromo-N—(N-BOC-(R)-valyl)-piperidine (COMPOUND B) is obtained and is separated by chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07612103B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-a93eca1b25e6407099f29547b42c5138 |
| Source note | uspto-grants-2009_11 |