HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,8-Diazabicyclo(5.4.0)undec-7-ene → HCID 68947314, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| Reactant | HCID 68948045 | HCID 68948045 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 68947314 | HCID 68947314 | — |
Reaction Steps
1.684 g of 3-acetoxy-4-bromo-N—(N-BOC-valyl)-piperidine dissolved in 4 ml of toluene are treated with 4 ml of DBU in a sealed tube and heated to 90°. The mixture obtained is treated with EE, extracted with aqueous HCl, washed and from the organic phase obtained solvent is evaporated. 3-Acetoxy-N—(N-BOC-(R)-valyl)-1,2,3,6-tetrahydropyridine is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07612103B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-b4d7d66932d6474da5c185fdef9100d9 |
| Source note | uspto-grants-2009_11 |