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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1432530Generated: November 2, 2026

Acetic Anhydride → N-(2,3-Dihydro-1H-inden-2-yl)acetamide

https://huagongshe.com/reaction/1432530

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AnhydrideHCID 7918—
ReactantEthyl AcetateHCID 8857—
Reactant2-Aminoindan hydrochlorideHCID 122764—
SolventTriethylamineHCID 8471—
ProductN-(2,3-Dihydro-1H-inden-2-yl)acetamideHCID 12452137—

Reaction Steps

Acetic anhydride (3.55 ml) was dropped to the mixture of 6.37 g 2-amino indane hydrochloride, 60 ml of ethyl acetate and 10.4 ml triethylamine and the reaction mixture was stirred at room temperature for 15 hours. The solvents were evaporated in vacuo and the solid residue was digested with water, filtered and dried at 40° C. in vacuo.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07612104B2
Source datasetuspto-grants-2009_11
ORD IDord-c3b963e7c5174af1af58ad6cbd78424d
Source noteuspto-grants-2009_11