HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2-Amino-indan-5-sulfonic acid (5-isopropyl-[1,3,4]thiadiazol-2-yl)-amide hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | N-[5-(5-Isopropyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-indan-2-yl]-acetamide | HCID 57933501 | — |
| Product | 2-Amino-indan-5-sulfonic acid (5-isopropyl-[1,3,4]thiadiazol-2-yl)-amide hydrochloride | HCID 67231283 | — |
Reaction Steps
N-[5-(5-Isopropyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-indan-2-yl]-acetamide (96 mg) was heated and stirred for 27 hours in 10 ml 2N hydrochloric acid at 100° C. After completion a clear solution occurred. This was evaporated to dryness and the solid residue was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07612104B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-195da3575622433db7aba25ba3d389bf |
| Source note | uspto-grants-2009_11 |