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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 143290Generated: October 26, 2026

Potassium Cation → 2,5-Difluoro-4-[2-(4-trifluoromethyl-phenyl)-4-(4-trifluoromethyl-piperidin-1-ylmethyl)-thiazol-5-ylmethoxy]-benzonitrile

https://huagongshe.com/reaction/143290

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CationHCID 813—
ReactantWaterHCID 962—
Reactanttert-ButanolHCID 6386—
ReactantTetrahydrofuranHCID 8028—
Reactant2,4,5-TrifluorobenzonitrileHCID 593813—
Reactant2-Methylpropan-2-olateHCID 4574913—
ReactantHCID 59556321HCID 59556321—
Product2,5-Difluoro-4-[2-(4-trifluoromethyl-phenyl)-4-(4-trifluoromethyl-piperidin-1-ylmethyl)-thiazol-5-ylmethoxy]-benzonitrileHCID 59594747—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-239ea055dd404ae087b288677fccf0f0
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)