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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 143293Generated: October 25, 2026

2,3-Dihydroxybutanedioic Acid → (2-Methyl-5-{1-[4-methyl-2-(4-trifluoromethyl-phenyl)-thiazole-5-carbonyl]-piperidin-3-yl}-phenoxy)-acetic acid ethyl ester

https://huagongshe.com/reaction/143293

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-Dihydroxybutanedioic AcidHCID 875—
ReactantDiethyl EtherHCID 3283—
ReactantEthyl AcetateHCID 8857—
Reactant1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 15908—
Reactant4-Methyl-2-(4-(trifluoromethyl)phenyl)-5-thiazolecarboxylic acidHCID 2775663—
ReactantEthyl 2-(2-methyl-5-piperidin-3-ylphenoxy)acetateHCID 68882512—
Product(2-Methyl-5-{1-[4-methyl-2-(4-trifluoromethyl-phenyl)-thiazole-5-carbonyl]-piperidin-3-yl}-phenoxy)-acetic acid ethyl esterHCID 68885433—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-164c3ae30acb470c8526261b9a91effc
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)