HCID 131727725, compound → HCID 90917862, compound

HRID 1433044Notes

Reaction equation

HRID 1433044 reaction equation
[CH2:1]([O:3][C:4](=[O:16])[CH2:5][O:6][C:7]1[CH:12]=[C:11]([Cl:13])[CH:10]=[CH:9][C:8]=1[CH2:14][OH:15])[CH3:2]>C(Cl)(Cl)Cl.[Mn+4]>[CH2:1]([O:3][C:4](=[O:16])[CH2:5][O:6][C:7]1[CH:12]=[C:11]([Cl:13])[CH:10]=[CH:9][C:8]=1[CH:14]=[O:15])[CH3:2]

Participants

4

Reactant 1

HCID 131727725HCID 131727725, compound

Product 1

HCID 90917862HCID 90917862, compoundYield 90%

Reagents, catalysts & solvents 2

HCID 178507069HCID 178507069, compoundCatalystHCID 6212ChloroformSolvent

Procedure

Ethyl-(2-hydroxymethyl-5-chloro-phenoxy)-acetate (2.44 g, 10 mmol) is dissolved in 40 ml of chloroform. Activated manganese (IV) oxyde (8.7 g, 100 mmol) is added in two portions and the resulting suspension is stirred at room temperature for 5 hours. After fitration on a pad of celite and concentration ethyl-(2-formyl-5-chloro-phenoxy)-acetate (2.18 g, 90% yield) is obtained as a pale yellow oil.

Sources & evidence

ORD record
ord-f21b69aecc214c65bdd2219e27301e6e
Source dataset
uspto-grants-2009_11
Patent number
US07612075B2

Reaction notes

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