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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 143316Generated: October 31, 2026

Dimethyl Sulfoxide → 4-[4-(4-Fluoro-3-trifluoromethyl-phenyl)-1-methyl-1H-imidazol-2-yl]-piperidine-1-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/143316

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethyl SulfoxideHCID 679—
ReactantPotassium CationHCID 813—
ReactantHydroxideHCID 961—
ReactantWaterHCID 962—
ReactantMethyl iodideHCID 6328—
ReactantHCID 178451792HCID 178451792—
Product4-[4-(4-Fluoro-3-trifluoromethyl-phenyl)-1-methyl-1H-imidazol-2-yl]-piperidine-1-carboxylic acid tert-butyl esterHCID 66649931—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-449ba402cac84f0496077f0785b94517
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)