4-(Trifluoromethyl)benzylamine → HCID 178506180, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 5-bromo-2-chloro-1H-benzoimidazole (0.100 g, 0.432 mmol) and 4-trifluoromethyl-benzylamine (0.8 mL) was heated in a microwave apparatus at 200° C. for 1 hour. The reaction mixture was cooled, and purified by chromatography (silica, hexanes: EtOAc, 1:1) to afford the title product as a white solid (0.101 g, 63%).

Provenance & Evidence