p-Toluenesulfonic acid → HCID 86608885, compound

Participants

Reaction Steps

A solution of p-toluene sulphonic acid (54 mg, 0.28 mmol) in acetonitrile (1 ml) was added to a suspension of (2S)-2-Amino-4-ethyl-2-methylhexanoic acid (50 mg, 0.28 mmol, Example 1) in acetonitrile (1 ml) and the mixture heated until dissolved. The solution was filtered whilst hot and allowed to cool overnight to give the title compound as fine white needles, (69 mg, 70%)

Provenance & Evidence