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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1433629Generated: November 1, 2026

4-(4-Nitrophenoxy)furo[2,3-b]pyridine-2-carboxylic acid methyl ester → 4-(4-Aminophenoxy)furo[2,3-b]pyridine-2-carboxylic acid methyl ester

https://huagongshe.com/reaction/1433629

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-Nitrophenoxy)furo[2,3-b]pyridine-2-carboxylic acid methyl esterHCID 58931497—
CatalystIronHCID 23925—
Product4-(4-Aminophenoxy)furo[2,3-b]pyridine-2-carboxylic acid methyl esterHCID 5893146286.9%

Reaction Steps

4-(4-Nitrophenoxy)-furo[2.3-b]pyridine-2-carboxylic acid methyl ester (70 mg) was subjected to iron reduction by the same method as in Production Example 10 to obtain the title compound (55 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07612092B2
Source datasetuspto-grants-2009_11
ORD IDord-725fa0a187514c8a8ab043ca8d831493
Source noteuspto-grants-2009_11