Ethylamine → HCID 58931406, compound

HRID 1433710Notes

Reaction equation

HRID 1433710 reaction equation
[F:1][C:2]1[CH:7]=[C:6]([O:8][C:9]2[C:18]3[C:13](=[CH:14][C:15]([O:23][CH3:24])=[C:16]([C:19]([O:21][CH3:22])=[O:20])[CH:17]=3)[N:12]=[CH:11][CH:10]=2)[CH:5]=[CH:4][C:3]=1[NH:25][C:26](=O)[O:27]C1C=CC=CC=1.[CH2:35]([NH2:37])[CH3:36]>CS(C)=O>[CH3:22][O:21][C:19]([C:16]1[CH:17]=[C:18]2[C:13](=[CH:14][C:15]=1[O:23][CH3:24])[N:12]=[CH:11][CH:10]=[C:9]2[O:8][C:6]1[CH:5]=[CH:4][C:3]([NH:25][C:26]([NH:37][CH2:35][CH3:36])=[O:27])=[C:2]([F:1])[CH:7]=1)=[O:20]

Participants

4

Reactant 2

HCID 6341EthylamineHCID 22936381HCID 22936381, compound

Product 1

HCID 58931406HCID 58931406, compound

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

Phenyl N-(2-fluoro-4-(7-methoxy-6-methoxycarbonyl-4-quinolyl)oxyphenyl)carbamate (0.9 g) was treated with ethylamine in dimethylsulfoxide at room temperature in the same manner as Example 11, to obtain the title compound (0.6 g) as a solid.

Sources & evidence

ORD record
ord-56cef1c5b54841b3a2133fc13b5d09b9
Source dataset
uspto-grants-2009_11
Patent number
US07612092B2

Reaction notes

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