Methanol → 3-Amino-4-{[5-(5-chloro-thiophen-2-yl)-isoxazol-3-ylmethyl]-amino}-benzoic acid methyl ester
Reaction equation
[BH4-:1].[CH3:29][OH:30].[CH3:3][O:4][C:5]([c:6]1[cH:7][c:8]([N+:25]([O-:26])=[O:27])[c:9]([NH:12][CH2:13][c:14]2[n:15][o:16][c:17](-[c:19]3[s:20][c:21]([Cl:24])[cH:22][cH:23]3)[cH:18]2)[cH:10][cH:11]1)=[O:28].[Cl:31][CH2:32][Cl:33].[Na+:2]>>[CH3:3][O:4][C:5]([c:6]1[cH:7][c:8]([NH2:25])[c:9]([NH:12][CH2:13][c:14]2[n:15][o:16][c:17](-[c:19]3[s:20][c:21]([Cl:24])[cH:22][cH:23]3)[cH:18]2)[cH:10][cH:11]1)=[O:28]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-a2cb1251b0f64254a9c0aabb1070fac8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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