huagongshe.com
HRID1433787

反应详情

EQUATION

反应方程式

HRID 1433787 的结构方程式

REACTANTS

反应物

3
结构：C[C@@H](OCc1ccccc1)[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O
HCID16213170

O-Benzyl-N-{[(9H-fluoren-9-yl)methoxy]carbonyl}-L-threonine

C26H25NO5

结构：CC(C)(C)OC(=O)N[C@@H](C(=O)O)c1ccc(OC[C@H]2COC(C)(C)O2)cc1
HCID67001404

未命名化合物

结构：C[C@@H](c1ccccc1)[C@H](NC(=O)[C@H](N)c1ccc(OC[C@H](O)CO)cc1)C(=O)Nc1ccc(I)cc1Cl
HCID69006543

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)[C@@H](C(=O)Nc1ccc(I)cc1Cl)N1C(=O)N[C@H](c2ccc(OCC3CC3)cc2)C1=O
HCID57935190

未命名化合物

PROCEDURE

实验过程

Prepared by the same method as described in example 3 except that (i) 2-chloro-4-iodo-aniline was used in place of 4-bromo-2-chloro-aniline in step 1, (ii) (S)-2-tert-butoxycarbonylamino-3-methyl-butyric acid was used in place of (S,S)-2-tert-butoxycarbonylamino-3-phenyl-butyric acid in step 1, and (iii) (R)-tert-butoxycarbonylamino-(4-cyclopropylmethoxy-phenyl)-acetic acid (prepared as described in example 109) was used in place of (R)-tert-butoxycarbonylamino-[4-(2-tert-butoxy-ethoxy)-phenyl]-acetic acid in step 2.

WORKUP

后处理

  1. customPrepared by the same method