HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-3-nitropyridine → 4-(6-Methoxynaphthalen-2-yl)pyridin-3-ylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-3-nitropyridine | HCID 2762920 | — |
| Reactant | 6-Methoxy-2-naphthaleneboronic acid | HCID 4641692 | — |
| Reactant | 4-(6-Methoxynaphthalen-2-yl)-3-nitropyridine | HCID 23087476 | — |
| Product | 4-(6-Methoxynaphthalen-2-yl)pyridin-3-ylamine | HCID 23087162 | 90.6% |
Reaction Steps
Synthesized from (6-methoxynaphthalen-2-yl)boronic acid and 4-bromo-3-nitropyridine according to an analogous synthetic method to Preparation Example 79, 4-(6-methoxynaphthalen-2-yl)-3-nitropyridine (2.1 g) was used according to an analogous synthetic method to Example 22 to provide the title compound (1.7 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07612114B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-459fbbf0f2974d6db6140f3e09219528 |
| Source note | uspto-grants-2009_11 |