HRID1434045

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID13174870

未命名化合物

结构：CCNc1cc2c(cc1C1CCc3cc(OC(=O)C(C)(C)C)ccc3C1)OCO2

HCID57934012

未命名化合物

PRODUCTS

生成物

结构：Oc1ccc2c(c1)CCC(c1cc3c(cc1NCCCc1ccc(OCCN4CCCCCC4)cc1)OCO3)C2

HCID66627184

未命名化合物

收率 76.5%

PROCEDURE

实验过程

Synthesized from pivalic acid 6-(6-ethylaminobenzo[1,3]dioxol-5-yl)-5,6,7,8-tetrahydronaphthalen-2-yl ester (40 mg) and 4-(2-azepan-1-ylethoxy)benzoic acid hydrochloride (80 mg) according to an analogous synthetic method to Example 337 described below, the title compound (42 mg) was obtained.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-9d9ecfe7757c43c2856b13a708c0d7dc
来源数据集: uspto-grants-2009_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07612114B2
来源说明: uspto-grants-2009_11

反应 SMILES

[CH2:1]([NH:3][C:4]1[C:5]([CH:13]2[CH2:22][CH2:21][C:20]3[CH:19]=[C:18]([O:23]C(=O)C(C)(C)C)[CH:17]=[CH:16][C:15]=3[CH2:14]2)=[CH:6][C:7]2[O:11][CH2:10][O:9][C:8]=2[CH:12]=1)[CH3:2].Cl.[N:31]1([CH2:38][CH2:39][O:40][C:41]2[CH:49]=[CH:48][C:44]([C:45](O)=O)=[CH:43][CH:42]=2)[CH2:37][CH2:36][CH2:35][CH2:34][CH2:33][CH2:32]1>>[N:31]1([CH2:38][CH2:39][O:40][C:41]2[CH:49]=[CH:48][C:44]([CH2:45][CH2:2][CH2:1][NH:3][C:4]3[C:5]([CH:13]4[CH2:14][CH2:15][C:16]5[CH:17]=[C:18]([OH:23])[CH:19]=[CH:20][C:21]=5[CH2:22]4)=[CH:6][C:7]4[O:11][CH2:10][O:9][C:8]=4[CH:12]=3)=[CH:43][CH:42]=2)[CH2:37][CH2:36][CH2:35][CH2:34][CH2:33][CH2:32]1