HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-(4-Bromo-2-fluorophenoxy)ethyl)piperidine → HCID 66627898, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-(4-Bromo-2-fluorophenoxy)ethyl)piperidine | HCID 23087072 | — |
| Reactant | HCID 23087231 | HCID 23087231 | — |
| Reactant | HCID 66627800 | HCID 66627800 | — |
| Product | HCID 66627898 | HCID 66627898 | 77.2% |
Reaction Steps
Synthesized from 5-methoxy-2-(6-methoxy-1,1-dimethyl-1,4-dihydronaphthalen-2-yl)phenylamine and 1-[2-(4-bromo-2-fluorophenoxy)ethyl]piperidine according to an analogous synthetic method to Example 116, [3-fluoro-4-(2-piperidin-1-ylethoxy)phenyl][5-methoxy-2-(6-methoxy-1,1-dimethyl-1,4-dihydronaphthalen-2-yl)phenyl]amine (439 mg) was used according to an analogous synthetic method to Example 111 to provide the title compound (303 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07612114B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-b2d41ebae0fd40f48c3d1b17b2cf633b |
| Source note | uspto-grants-2009_11 |