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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1434076Generated: November 1, 2026

1-(2-(4-Bromo-2-fluorophenoxy)ethyl)piperidine → HCID 66627898, compound

https://huagongshe.com/reaction/1434076

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-(4-Bromo-2-fluorophenoxy)ethyl)piperidineHCID 23087072—
ReactantHCID 23087231HCID 23087231—
ReactantHCID 66627800HCID 66627800—
ProductHCID 66627898HCID 6662789877.2%

Reaction Steps

Synthesized from 5-methoxy-2-(6-methoxy-1,1-dimethyl-1,4-dihydronaphthalen-2-yl)phenylamine and 1-[2-(4-bromo-2-fluorophenoxy)ethyl]piperidine according to an analogous synthetic method to Example 116, [3-fluoro-4-(2-piperidin-1-ylethoxy)phenyl][5-methoxy-2-(6-methoxy-1,1-dimethyl-1,4-dihydronaphthalen-2-yl)phenyl]amine (439 mg) was used according to an analogous synthetic method to Example 111 to provide the title compound (303 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07612114B2
Source datasetuspto-grants-2009_11
ORD IDord-b2d41ebae0fd40f48c3d1b17b2cf633b
Source noteuspto-grants-2009_11