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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1434084Generated: November 2, 2026

4-(2-Azepan-1-ylethoxy)benzoic acid hydrochloride → HCID 66627213, compound

https://huagongshe.com/reaction/1434084

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(2-Azepan-1-ylethoxy)benzoic acid hydrochlorideHCID 13174870—
ReactantHCID 23087080HCID 23087080—
ReactantHCID 66626444HCID 66626444—
ProductHCID 66627213HCID 66627213—

Reaction Steps

Synthesized from 2-(7-methoxy-2,2-dimethylchroman-3-yl)phenylamine and 4-(2-azepan-1-ylethoxy)benzoic acid hydrochloride according to an analogous synthetic method to Example 152, [4-(2-azepan-1-ylethoxy)benzyl][2-(7-methoxy-2,2-dimethylchroman-3-yl)phenyl]amine (473 mg) was used according to an analogous synthetic method to Example 36 to provide [4-(2-azepan-1-ylethoxy)benzyl]ethyl[2-(7-methoxy-2,2-dimethylchroman-3-yl)phenyl]amine (472 mg). This compound (470 mg) was used according to an analogous synthetic method to Example 111 to provide the title compound (200 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07612114B2
Source datasetuspto-grants-2009_11
ORD IDord-3d3f61d7af8445248ee57dca15d170b3
Source noteuspto-grants-2009_11