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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1434097Generated: November 1, 2026

4-(2-Azepan-1-ylethoxy)benzoic acid hydrochloride → HCID 66627036, compound

https://huagongshe.com/reaction/1434097

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(2-Azepan-1-ylethoxy)benzoic acid hydrochlorideHCID 13174870—
ReactantHCID 23087244HCID 23087244—
ReactantHCID 66626992HCID 66626992—
ProductHCID 66627036HCID 66627036—

Reaction Steps

Synthesized from 5-methoxy-2-[1-(3-methoxyphenyl)pyrrolidin-3-yl]phenylamine and 4-(2-azepan-1-ylethoxy)benzoic acid hydrochloride according to an analogous synthetic method to Example 152, [4-(2-azepan-1-ylethoxy)benzyl]{5-methoxy-2-[1-(3-methoxyphenyl)pyrrolidin-3-yl]phenyl}amine (202 mg) was used according to an analogous synthetic method to Example 36 to provide [4-(2-azepan-1-ylethoxy)benzyl]ethyl{5-methoxy-2-[1-(3-methoxyphenyl) pyrrolidin-3-yl]phenyl}amine (188 mg). The total amount of this compound was used according to an analogous synthetic method to Example 111 to provide the title compound (153 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07612114B2
Source datasetuspto-grants-2009_11
ORD IDord-e7d6813e353e4876bf5db0b870918a85
Source noteuspto-grants-2009_11