HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 57933923, compound → 6-{2-{{2-[4-(2-Azepan-1-ylethoxy)phenyl]ethyl}ethylamino}-4-hydroxyphenyl}-5,6,7,8-tetrahydronaphthalen-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 57933923 | HCID 57933923 | — |
| Reactant | {2-[4-(2-Azepan-1-ylethoxy)phenyl]ethyl}ethyl[5-methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]amine | HCID 66625874 | — |
| Product | 6-{2-{{2-[4-(2-Azepan-1-ylethoxy)phenyl]ethyl}ethylamino}-4-hydroxyphenyl}-5,6,7,8-tetrahydronaphthalen-2-ol | HCID 57934127 | 77% |
Reaction Steps
Synthesized from {2-[4-(2-azepan-1-ylethoxy)phenyl]ethyl}[5-methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]amine according to an analogous synthetic method to Example 36, {2-[4-(2-azepan-1-ylethoxy)phenyl]ethyl}ethyl[5-methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]amine (130 mg) was used according to an analogous synthetic method to Example 111 to provide the title compound (95 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07612114B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-4907704d936e454f84c2de01e6916e30 |
| Source note | uspto-grants-2009_11 |