huagongshe.com
HRID1434164

反应详情

EQUATION

反应方程式

HRID 1434164 的结构方程式

REACTANTS

反应物

2
结构：CN(C)C(=O)CCl
HCID75886

2-Chloro-N,N-dimethylacetamide

C4H8ClNO

结构：CCN(C(=O)c1ccc(O)cn1)c1cc(OC)ccc1C1CCc2cc(OC(=O)C(C)(C)C)ccc2C1
HCID57934579

未命名化合物

PRODUCTS

生成物

1
结构：CCN(Cc1ccc(OCCN(C)C)cn1)c1cc(OC)ccc1C1CCc2cc(O)ccc2C1
HCID57934478

未命名化合物

收率 101.4%

PROCEDURE

实验过程

Synthesized from pivalic acid 6-{2-[ethyl(5-hydroxypyridine-2-carbonyl)amino]-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen-2-yl ester (25 mg) and 2-chloro-N,N-dimethylacetamide (12 mg) following the synthetic method of Example 404 described below and purified by LC-MS, the title compound (24 mg) was obtained. ESI-Mass; 476 [M++H]

WORKUP

后处理

  1. custompurified by LC-MS